Best Ergonomic Mouse For Wrist Pain

If you are in a hurry and just want to find out what the best ergonomic mouse for wrist pain is, then we recommend the Anker 2.4G Wireless Vertical Ergonomic Optical Mouse as the best one.

If you’re using the computer on a regular basis, then you might have suffered from minor wrist pain. It usually occurs because of prolonged use of the computer and improper wrist and hand position. 

It might seem normal and fine if it doesn’t happen all the time, but getting constant wrist and arm pain can sometimes lead to severe cases of carpal tunnel syndrome.

One way to avoid injuring your arm aside from resting is to use an ergonomic mouse instead. An ergonomic mouse is a mouse that is specially designed to allow a neutral hand position when holding the mouse. This gives your hand and arms a more comfortable and relaxed position.

You won’t have to deal with uncomfortable shoulder, hand, or wrist strains because an ergonomic mouse was designed to give you a better and healthier way to use the mouse. 

It lowers the chances of injuring your wrist or hurting any part of your arm because of its efficiency and design.

Whether you’re a frequent computer user or not, using an ergonomic mouse can definitely benefit you. From gamers to everyday office workers, an ergonomic mouse can be used by anyone.

* This post may contain Amazon affiliate links and as an Amazon Associate, I earn from qualifying purchases.

At A Glance: Best Ergonomic Mouse For Wrist Pain 

Mouse Best For Type Weight Ratings
Anker 2.4G Wireless Vertical Ergonomic Optical Mouse Best Wireless Vertical Mouse Wireless 3.4 oz 9.8/10
Tecknet Wired Optical Computer Gaming Mouse Best Wired Gaming Mouse Wired 4.00 oz 9.7/10
Microsoft Sculpt Ergonomic Mouse (L6V-00001) Best Ergonomic Mouse for Thumb Wireless 8 ounces 9.3/10
Tecknet Pro 2.4G Ergonomic Wireless Mobile Optical Mouse with USB Nano Best Ergonomic Mouse for Wrist Strain Wireless 3.00 ounces 9.4/10
Logitech Trackman Marble Trackball Mouse Best Ergonomic Trackball Mouse Wired 10.4 ounces 9.3/10

Ergonomic Mouse For Wrist Pain Reviews

Now that you’ve figured what to consider before purchasing an ergonomic mouse, here’s a list of the five best ergonomic mouse money can buy.

Anker 2.4G Wireless Vertical Ergonomic Optical Mouse

Best Wireless Vertical Mouse

If it’s your first time purchasing an ergonomic mouse, you won’t go wrong with the Anker 2.4G Wireless Vertical Ergonomic Optical Mouse. 

It’s a mouse with a lot of features to choose from. You won’t have a hard time configuring and getting used to this trustworthy mouse.

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  • Scientific ergonomic design
  • 800 / 1200 / 1600 DPI Resolution Optical Tracking Technology
  • Includes next/previous buttons
  • Power Saving Mode included
  • Black futuristic design
  • Compatible with Windows 10, 8, 7, Vista, XP, 2000, Linux and Mac OS X
  • Wireless
  • Includes an instruction manual
  • 18-month hassle-free warranty included
  • Shipping weight of 7.2 ounces


One of the best things about this ergonomic mouse is its powerful optical tracking technology. You won’t have any trouble with its sensor. 

You can choose from 800, 1200, or 1600 DPI resolutions to measure how fast or slow you’d want your cursor to work. Accuracy and precision certainly come when you decide to use the Anker.

Aside from its state-of-the-art tracking technology, the Anker also provides a smooth and seamless performance. It doesn’t matter if it’s a rough or uneven surface, this ergonomic mouse can handle it.

In terms of design, it’s certainly sleek, futuristic, and functional. It has a neutral “handshake” wrist and arm position that gives the user a relaxed feel. You’ll have no trouble with using this for long hours because you’ll be having the correct arm alignment.

With a wireless feature, you’re sure to never have another messy situation with this handy mouse. The Anker is durable, functional, and compatible with most operating systems.

For easy set-up, the Anker includes an instruction manual to get you started on your ergonomic use.


  • Incompatibility with Mac OS X El Capitan
  • 2 AAA batteries not included


The Anker 2.4G Wireless Vertical Ergonomic Optical Mouse is a good choice for anyone looking for a reliable ergonomic mouse. It has a unique, vertical design that gives its user absolute comfort.

You won’t have to worry about sudden wrist pains or the risk of having carpal tunnel syndrome. This trusty mouse assures comfort and ease of use. Just be sure your computer is compatible with the mouse, otherwise, you can’t properly use it.

The Anker is an affordable and high-quality ergonomic mouse that can be used by anyone who constantly spends his or her time using the computer. 

Gamers, designers, and all sorts of people can benefit from the use of this premium ergonomic mouse.

Read the full review

Tecknet Wired Optical Computer Gaming Mouse

Best Wired Gaming Mouse

Gamers all over have enjoyed the use of this trusty gaming mouse. It’s a mouse built with style, comfort, and all-around functionality.

If you’re someone who spends long hours in front of the computer playing Counter-Strike, Minecraft, or DoTA, then you’ll have a swell time with this mouse’s performance.

For the past few years, Tecknet has been making durable and well-designed consumer electronics equipment. It’s no surprise that their Wired Optical Gaming Mouse is a great choice for gamers and non-gamers alike.

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  • Strong 2000 DPI Optical Sensor
  • 3 DPI settings (1000 / 1600 / 2000)
  • Sleek ergonomic design
  • Premium quality
  • Compatible with Windows 98, 2000, ME, XP, Vista, 7 and 8
  • Easy fit on the hand
  • Six handy buttons
  • Nonslip shape
  • Wired, USB
  • Responsive tracking
  • Runs on 1 AA battery
  • Comes in a bronze color with discreet blue lines
  • Shipping weight of 6.4 ounces


Deliberately designed for gamers, the Tecknet Wired Optical Computer Gaming Mouse is reliable and features an easy-grip and non-slip shape to make it easy and comfortable. 

You won’t have problems shooting, aiming, or even attacking your opponent nonstop because this nifty ergonomic mouse was designed for an optimized gaming experience.

It has a fast-tracking technology that gives a seamless performance. Getting delays during a game won’t happen because of the mouse’s precision and accuracy. 

It has a powerful DPI setting up to 2000. You can make the sensor slower by adjusting it to 1600 or 1000. It all depends on you.

Most gaming mice tend to be light, that’s why the Tecknet was given an extra 40g of weight to have that quality compact feel. This gives it a light yet solid feel. 

The mouse works on most operating systems and offers a variety of buttons to help in gaming performance.


The mouse is completely smooth, there was no rubber or rough texture to help in hand grip

Buttons aren’t programmable


If you’re a veteran gamer who spends more than 8 hours a day practicing your skills in computer games, chances are you’re going to enjoy this one-of-a-kind gaming mouse.

Tecknet is an affordable choice for anyone who wants to change his or her typical ways of using the mouse.

The Tecknet Wired Optical Computer Gaming Mouse provides a comfortable and easy grip with its stylish and compact design. There are some issues but that’s mostly due to preferences. 

Some users preferred it to have more features, but that doesn’t mean the Tecknet is anything less than the best.

It’s a good choice for anyone who wants to have a healthier computer gaming experience.

Read the full review

Microsoft Sculpt Ergonomic Mouse (L6V-00001)

Best Ergonomic Mouse for Thumb

Microsoft has been known for creating one of the best computer systems in the world. It’s responsible for most of the computers you see all around you.

It’s a trusted brand that not only provides great computer equipment but also a superb range of computer accessories.

One of those accessories happens to be this gem of an ergonomic mouse, the Microsoft Sculpt L6V-00001.

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  • Streamlined Curves for maximized comfort
  • Simple Navigation
  • Advanced Ergonomic Design
  • Equipped with Microsoft BlueTrack Technology
  • Four-Way Scrolling
  • Sleek Design
  • Thumb Scoop
  • Back Button included
  • Windows Button for easy access to the Start Screen
  • Length: 3.87”
  • Width: 2.23”
  • 2 AA alkaline batteries (included)
  • The battery life of up to 12 months
  • USB 2.0 compatible
  • Compatible with: Windows 10, Windows 8, Windows 7, Macintosh OX X versions 10.7-10.9 and Android 3.2 and 4.2
  • Shipping weight of 12 ounces


When it comes to being a die-hard Microsoft fan, you’re bound to invest your money on something obviously Microsoft-related.

Luckily for you or for anyone who loves Microsoft, they’ve manufactured an excellent ergonomic mouse that can fit well in the palm of your hand. It has a set of features that can make your use of the computer easier and so much more enjoyable.

It’s designed in a unique shape to give you that comfortable feel. It has a thumb scoop to maintain the correct hand and wrist position without worrying about long hours of use.

Microsoft has been kind to its users by adding easier access to the Start Screen. There’s a button on the mouse that’s specifically designed to get through the Start Screen by simply clicking on it.

There’s no need to move your mouse on the lower-left corner of the screen, just click using your right hand and you can easily navigate what you need to do there.

Aside from that, it also features a unique four-way scroll that lets you go up, down, left, or right.


  • Can’t work on clear glass or mirrored surfaces
  • Advanced functions aren’t available for every operating system
  • Not available for left-handed users
  • A bit expensive


The Microsoft Sculpt L6V-00001 packs a ton of features that not every software or mouse can compete with. If you’re a Microsoft user then this mouse is definitely made for you. 

It’s a great mouse to use and perhaps the best ergonomic mouse Microsoft has ever designed. It can provide comfort, functionality, and long-lasting longevity.

Before purchasing, just be sure your table isn’t made of glass. Otherwise, you wouldn’t be able to use the mouse’s full potential. 

It’s also a bit more expensive compared to other mice, but the features and the high standards Microsoft designed are worth it.

Read the full review

Tecknet Pro 2.4G Ergonomic Wireless Mobile Optical Mouse with USB Nano

Best Ergonomic Mouse for Wrist Strain

Another premium ergonomic mouse from Tecknet is this well-designed wireless mouse that offers state-of-the-art technology Tecknet. 

There are a lot of features to take in with this compact ergonomic mouse.

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  • Includes a small USB Nano Receiver
  • Three adjustable DPI Levels (2400 / 1600 / 1000)
  • TeckNet Tru-Wave Technology
  • TeckNet Co-Link Technology
  • Wireless
  • Compatible with Windows XP, Vista, 7, 8, 8.1, 10, Mac, and Linux.
  • Smart auto-sleep mode
  • Long battery life up to 24 months
  • Includes a battery life indicator
  • Includes a Back and Forth button
  • Available in different colors
  • Includes a user documentation
  • Runs on 2 AAA batteries
  • Shipping weight of 4 ounces


What makes the TeckNet Pro easy to use is its Plug and Play feature. It’s easy to operate its USB Nano receiver and you’ll be able to use your mouse in no time.

If you’re looking for a powerful DPI setting, then this one’s definitely for you. You can adjust the DPI setting up to 2400 and lower it by 1600 or 1000. This gives you more ways to decide on how fast or how slow you would want your cursor to respond.

The TeckNet Pro also features a comfortable and contoured ergonomic design that makes it absolutely pleasant for anyone to use.

There’s no need to worry about wrist strain because this handy mouse assures you that you’re not getting any form of pain in your hand.

With its design, it features the TeckNet Tru Wave and TeckNet Co-Link technology that provides accuracy and precision when using the mouse. 

It’s also a way for establishing an easy connection with other devices without the need to reconnect it again.

Compatibility is available for almost all Windows operating systems and Mac and Linux.


  • Size could be bigger
  • Button placement could improve
  • Battery life depends on user consumption


If you’re looking for something to replace your mouse, then the Tecknet Pro 2.4G Ergonomic Wireless Mouse is a good choice. It’s recommended for people who want to avoid wrist strain and the risk of carpal tunnel syndrome.

It’s a comfortable and easy way to use the mouse. It might not be perfect, but it works amazingly.

The TeckNet Pro is a wonderful ergonomic mouse for people who want to have an easier time using the mouse without the cost.

Size might be an issue, so check if your hand fits the mouse to be perfectly sure. The Tecknet Pro offers a wide array of features and a durable design that’s sure to withstand everyday use.

Read the full review

Logitech Trackman Marble Trackball Mouse

Best Ergonomic Trackball Mouse

Logitech is a popular brand to go to when searching for computer accessories. It’s been making durable computer equipment for decades and delivers high-quality equipment until today. 

If you’re looking for an ergonomic mouse you can trust your comfort on, then you’re on the right product.

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  • Optical Sensor technology
  • Ambidextrous design
  • Large, fingertip-controlled trackball
  • Contoured shape
  • Exceptional comfort
  • Stable base
  • Includes back/forward buttons
  • Patented Marble optical technology for smooth tracking
  • Compatible with Windows Vista, Windows 7, Windows 8, Windows 10, Mac OS X 10.5 or later, and Chrome OS
  • Includes a quick start guide
  • Shipping weight of 12.6 ounces


Perhaps the best thing about the Logitech TrackMan Marble is its ambidextrous design. Not all mice offer this kind of feature but the TrackMan Marble does.

This makes it available for left-handed users. They won’t have a problem adjusting to the feel of the mouse because it’s designed for them too.

This handy mouse features a fingertip-based control that provides comfort and reduces wrist fatigue. You won’t have to worry about spending long hours using your mouse because it’s assured to give you a relaxed and snug fit.

Tracking is also done effortlessly with this amazing mouse because of its reliability and precise performance. Logitech designed a trackball that works perfectly for this well-designed mouse. 

It has web surfing buttons that make it easy to navigate your way to a web page and two control buttons that give a faster forward and backward control.


  • Doesn’t work on clear glass or mirror surfaces
  • No scroll wheel


The Logitech TrackMan Marble mouse is one of the best ergonomic mice in the industry. It offers a lot of high-functioning features and gives a fast and reliable performance.

Wrist strain will surely be avoided when you use this mouse. Because of its ambidextrous design, you don’t have to worry about being left or right-handed because it works for both orientations.

The lack of a scroll wheel might take some time to get used to, but that doesn’t make the mouse perform any less. It has an affordable price and a quick and sensitive sensor that’s sure to give you easy navigation.

Read the full review

People Who Would Use an Ergonomic Mouse


Computer games range from first-person shooting games to complex role-playing games. Games cannot only be a way to relax but also as a form of competition. 

Professional gamers are ones who spend constant hours in front of the computer to practice their skills. 

With constant practice comes the risk of wrist pain, so using an ergonomic mouse provides a more natural hand and wrist position. This reduces the risk of wrist and other hand strains.

Designers / Photo Editors

Gamers aren’t the only ones who use the computer on a daily basis. 

Designers who need to work on the computer to use Adobe Photoshop or Illustrator all know the importance of having a good mouse to properly control the tools. 

An ergonomic mouse is essential in assuring longer longevity and an easier way to design.

Computer Programmers

It’s no surprise that computer programmers use the computer daily. They’d need to crack codes or debug different sites depending on their job description. 

This tends to put constant strain on their hands, so it’d be best for them to invest in a mouse they’re comfortable with. An ergonomic mouse is the best choice for them to prevent wrist strain.

Everyday Office Worker

It doesn’t matter if you’re a gamer or designer or computer programmer, the fact that you’re using the computer on a regular basis provides a risk for your wrist. 

Using the computer often adds strain and fatigue to your hands. In order to avoid unnecessary pains on your arms, be sure to use an ergonomic mouse that fits perfectly in your hand.

Features to Consider

Size and shape

The goal of an ergonomic mouse is to ensure you’re comfortable using it. If the mouse isn’t on the right side of your hand, you might experience discomfort despite how well it works. 

Always consider the mouse’s size before purchasing to assure a relaxed and compact fit.

Ambidextrous design

If you’re left-handed, chances are you might have a harder time finding the right ergonomic mouse for you. 

Always take note if the mouse can be used for left-handed users to assure you a better grip and easier usage. For sure, you can’t possibly use a mouse if you’re dominantly left-handed.

Amount of buttons

Ergonomic mice differ from one another, but they usually have different buttons for different purposes. Some mice have five buttons while some can have as many as eight.

It might be useful for most people but some people might find it bothersome especially if the buttons aren’t placed where they want them to. 

For example, it might hit their forefinger without them meaning to.

DPI Settings

The DPI is responsible for how sensitive your mouse cursor is. It determines how fast or how slow it moves. 

This is important for people who are particular with speed and precision especially when it comes to gaming and editing photos. The higher the DPI, then the faster your cursor can move.


Naturally, whatever ergonomic mouse you decide on will depend on your needs and purposes. 

However, if I had to pick an overall, general-purpose favorite among these, I would say the best ergonomic mouse is the Anker 2.4G Wireless Vertical Ergonomic Optical Mouse.

Its affordability and ease of use make it a great choice for all sorts of people who use the mouse in their everyday lives. 

It has a great tracking technology that won’t let you down and a futuristic design that’s sure to last you long on the computer.